成人阻塞性睡眠呼吸暂停低通气综合征缺氧程度的评估
周金玲* 陈天明 金明 杨锁平
【摘要】目的 评估阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者夜间缺氧程度。方法 收集在我科诊治的225例OSAHS患者，记录患者呼吸暂停低通气指数（AHI）、呼吸暂停时间（AT）、低通气时间（HT）、呼吸暂停低通气时间指数（AHTI）、氧减指数（ODI）、最低血氧饱和度（MiniSO2）、平均血氧饱和度、氧饱和度低于90%的时间占监测时间的百分比（TS90%）、Epworth嗜睡评分（ESS），并进行相关分析。结果 根据AHI划分OSAHS病情严重程度，以5次/h≤AHI＜15次/h为轻度OSAHS组，15次/h≤AHI＜30次/h为中度OSAHS组，AHI≥30次/h为重度OSAHS组。各组ODI,平均血氧饱和度，MiniSO2，Ts90%差异有统计学意义（P<0.001）， ODI，Ts90%，平均血氧饱和度，MiniSO2与AHI的相关系数r分别为0.862,0.649，-0.536，-0.649。结论 OSAHS患者缺氧严重程度的评估需结合ODI、Ts90%、平均血氧饱和度、MiniSO2综合判断。
【关键词】睡眠呼吸暂停，阻塞性，低氧血症，氧减指数，血氧饱和度
The Evaluation of the Severity of Nocturnal Oxygen Desaturation of Patients with Obstructive Sleep Apnea Hypopnea Syndrome. Zhou Jinling, Chen Tianming, Jin Ming, Yang Suoping. Department of Respiratory Medicine, The First People’s Hospital of Jingmen, Hubei province, 448000,China
【Abstract】Objective To evaluate the severity of oxgen desaturation of patient with obstructive sleep apnea hypopnea syndrome(OSAHS).Method To record data of 225 patients with OSAHS in First People’s Hospital of Jingmen, including Apnea-hypopnea index(AHI), apnea time (AT), hypopnea time(HT), oxygen desaturation index (ODI),minimum oxygen saturation (MiniSO2), TS90% and Epworth Sleepiness Scores were analyzed. Result The severity of OSAHS based on AHI was divided into three groups, mild group with 5/h≤AHI＜15/h, moderate group with 15/h≤AHI＜30/h, and severe group with AHI≥30/h. In each group, average oxygen saturation, MiniSO2, ODI and TS90% have statistical significance P<0.001, and separately r with AHI were -0.536，0.649，0.862,-0.649. Conclusion The best method of expressing the severity of oxygen desaturation of patients with OSAHS need the combination of several indices of oxygen desaturation(average oxygen saturation, MiniSO2, ODI, TS90%).
【Key words】Sleep apnea; Obstructive; Hypoxemia; Oxygen desaturation index; Oxygen saturation